Media reported some structures had collapsed and the Clark International Airport, a former USA military base, had suffered some damage and had closed.
Pampanga Gov. Lilia Pineda said the tremor caused power outages and damaged roadways near the epicenter.
She said 20 persons have so far been rescued from the collapsed supermarket and brought to the nearest hospital.
NGCP said it is still assessing the extent of the damage caused by the quake.
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Social media users on the northern island posted photos of the damage caused by the quake, including cracked walls and swinging light fixtures.
Jaime Melo, president of the Clark International Airport Corporation, said seven people suffered minor injuries when part of the ceiling at the check-in lobby of a passenger terminal collapsed, according to the Philippine News Agency.
After the natural disaster struck the capital, Manila, hundreds of office workers dashed out of buildings in panic, some wearing hard hats, and residents ran out of houses. Among those trapped were customers and employees of a grocery on the building's ground floor, she said.
Pineda said she had received reports that the quake left at least eight people dead in her province, a rice-growing agricultural region, but could not provide details.
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The quake was centred on the town of Castillejos, about 100 kilometres (62 miles) northwest of Manila, local geologists said.
Scientists from the US Geological Survey logged its magnitude at 6.3, and said its epicentre was 40 kilometres below the Earth's surface.
The quake prompted many residents to flee their homes and interrupted Manila train service.
The Philippines is part of the Pacific "Ring of Fire" - a zone of major seismic activity which has one of the world's most active fault lines.
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