South Africa's Temba Bavuma was left stranded on 95 not out as they tightened their grip on a first home series win over a scandal-hit Australia in nearly 50 years at tea on the second day of the fourth and final test at the Wanderers on Saturday.
Dean Elgar was the man that held things together after the fall of the de Villiers wicket, making a patient 39 from 158 balls.
The lead should already be enough for this Proteas team to enter the record books as they are now all but guaranteed to become the first South Africa side to win a Test series at home against the Aussies since re-admission. Joe Burns and Matt Renshaw opened, the first time Australia had switched both openers from the previous Test since the start of the 2013 Ashes, when Chris Rogers and Shane Watson walked out first.
Australia suffered twin collapses in the final session - 3-28 and 3-6 - to hand the ascendancy to South Africa, who look hell-bent on not letting it slip.
Usman Khawaja's half century was the only bright spot for Australia.
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After picking up three wickets on the opening day after bowling his heart out, Cummins continued in the same vein on Saturday.
But Markram brought up by the ton and in the evening session, after De Villiers had given Lyon the workaround with two fours and a six, he accrued a maiden 150 in Test cricket - a drive for four through mid-off from Cummins taking him to the tally.
Markram, though, was the star on a day when players and spectators alike seemed to have tried to move on from the controversy and bad feeling which resulted in three Australian players, including sacked captain Steve Smith, being banned and banished for ball-tampering in the third Test at Cape Town last weekend.
New Australia captain Tim Paine had complained after the opening day that his side were "flat" at times and they appeared so again, the usual intensity in their performance visibly lacking.
Cummins was not given out initially, but South Africa skipper Faf du Plessis reviewed the decision. But Cummins found the energy to remove Markram and South Africa captain Faf du Plessis in the space of two balls, du Plessis for a first-ball duck.
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Cummins has been Australia's best bowler on this tour and when he removed Maharaj with his fourth ball of the over, the Wanderers crowd stood standing as the left-arm spinner left the ground and No.11 Morne Morkel - playing in his final Test - entered it.
BOWLING: Hazlewood 26-3-86-0, Sayers 35-9-78-2, Cummins 28.5-5-83-5 (1w), Lyon 40-3-182-3, M. Marsh 6-1-30-0, Renshaw 1-0-4-0.
But unfortunately for the elegant left-hander his stay was cut short by a brilliant catch by de Kock, who crabbed down the leg-side to take Khawaja's glance off Philander whilst up to the stumps.
The usually pugnacious batsman, 31, repeatedly struggled to talk and tears ran down his face as he apologised to fans, team-mates, his family and the Australian public.
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