Malala began her campaign aged just 11, when she started writing a blog - under a pseudonym - for the BBC's Urdu service in 2009 about life under the Taliban in Swat, where they were banning girls' education.
Yousafzai entered her childhood home Saturday accompanied by her father, mother and brother.
Asked if she had any plans to join politics in Pakistan, Yousafzai said "I have no intentions right now of politics".
She received initial treatment in Pakistan and was later taken to Britain, where she continued her education and went on to win the 2014 Nobel Peace Prize, becoming the youngest-ever prize victor and garnering worldwide renown.
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Pakistan's Nobel Peace Prize victor Malala Yousafzai has returned to her hometown of Mingora in the Swat Valley for the first time since 2012.
Malate arrived on Thursday to Islamabad for a four-day visit under strong security measures and was received by Prime Minister Shahid Khaqan Abasi. "Islam has taught me the importance of peace".
Many Swat residents, including family friend Jawad Iqbal, were hopeful Malala would be able to return on this trip. "Always it has been my dream that I should go to Pakistan and there, in peace and without any fear, I can move on streets, I can meet people, I can talk to people".
Barkat Ali, 66, says he remembers holding Malala in his lap when she was a child in Mingora.
A hospital, being built by Malala Fund, will enable women in her hometown to get treatment in their locality instead of travelling outside the village, she said. "I've never been so happy before", she said of returning to Pakistan.
A group of private schools in Pakistan declared Friday to be "I Am Not Malala Day", for what its spokesman described as her "anti-Islam and anti-Pakistan ideology".
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The Taleban claimed responsibility in 2012 for the attack on Ms Yousafzai for her outspoken advocacy for girls' education, which was forbidden under the militants' rule over Swat. She has also written a book, spoken at the United Nations and met with refugees.
Yousafzai is widely respected internationally, but opinion is divided in Pakistan, where some conservatives view her as a Western agent.
"We will have to work very hard to bring them all to school", she vowed.
Her comments came after she broke down in tears as she delivered a speech on Thursday where she said that it was a "dream" to be back in the country after so many years.
"So much joy seeing my family home, visiting friends and putting my feet on this soil again", she wrote on a second tweet.
She said that people in Pakistan's Federally Administered Tribal Areas should be given equal their rights and supported the region's merger with adjacent Khyber Pakhtunkhwa province.
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