The bomb blast, which took place during the Friday prayers, is suspected to have been triggered by Improvised Explosive Device, IED, at the Saad Ben Obadah in Libya.
Libyan officials say twin bomb explosions at a mosque in the city of Benghazi have killed at least two people and wounded 75 others.
Mutaz al-Mu'tri, Benghazi's security directorate spokesperson, said two bomb bags had been used in the attack, according to Libya's 218 tv news channel.
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Later, the United Nations Support Mission in Libya condemned the attack in a statement.
"This heinous act should not provide a justification for revenge attacks".
"Direct or indiscriminate attacks against civilians are prohibited under global humanitarian law and constitute war crimes", the mission added, calling for "prompt, impartial investigations to bring perpetrators to justice".
Benghazi is controlled by the Libyan National Army (LNA), the dominant force in eastern Libya led by commander Khalifa Haftar. The LNA has been battling Islamists, including some linked to Daesh and al-Qaeda.
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Haftar, who opposes a UN-backed unity government based in Tripoli, announced Benghazi's "liberation" from jihadists in July last year after a three-year campaign, but sporadic violence has continued.
In the past few months there have been occasional, smaller scale bombings apparently targeting LNA allies or supporters.
The UN has been trying to mediate for years, hoping elections could help stabilise Libya. The country has been since split between rival governments and militias.
It has since imposed strict military control on the city and other parts of eastern Libya under its control.
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