Train derails in horror crash with multiple casualties feared

Amtrak engineer killed in train crash was 'a loving father'

2 dead, more than 100 hurt in South Carolina train crash

An Amtrak train en route from NY to Miami collided with a CSX freight train and derailed near Columbia, South Carolina, leaving at least two dead and 70 injured, police and Amtrak officials said.

An Amtrak train travelling from NY to Miami has derailed after crashing into a freight train in South Carolina, US.

Lexington Sheriff department said on Twitter that 50 people had been transferred to hospital, and that officers were on the scene, with local Red Cross volunteers also attending.

The derailment happened in Cayce, outside of South Carolina's capital of Columbia.

The train was carrying 147 passengers from NY to Miami before the fatal crash at roughly 2.30am.

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In January, again, Amtrak train ran into a garbage truck in Virginia, where a man died.

He added that no passengers or crew remained on the train. At this time, there are no passengers on the train. According to reports, the train had about 140 passengers and eight crew members on board when the crash occurred.

Republicans had chartered the train to carry them from Washington to the Greenbrier resort in West Virginia, where the party was holding its annual policy retreat.

The National Transportation Safety Board said it is deploying investigators to the scene.

Michael Kempf, the 54-year-old train engineer from Savannah, Georgia, was killed in the crash, she said.

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Anyone who believes they may have had loved ones onboard the train are urged to call Amtrak at 800-523-9101.

In December, an Amtrak train derailed in the northwestern US state of Washington, killing three people and injured dozens.

Lexington County coroner Margaret Fisher confirmed the fatalities in an email to the Associated Press.

The NTSB and other officials continue to investigate and work through the details of an Amtrak train crash in Cayce Sunday.

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