Last July, Iraqi forces liberated the northern city of Mosul, Iraq's second largest city, considered the de facto capital of the Islamic State group in Iraq.
"The heroic legions are advancing into the last den of terrorism in Iraq to liberate Al-Qaim, Rawa and the surrounding villages and hamlets", Prime Minister Haider Al-Abadi said.
The Iraqi air force has dropped thousands of pamphlets urging ISIS members in the border region to surrender.
"Tell those among your children and relatives who took up a weapon against the state to throw it aside immediately, and to go to any house on top of which a white flag has been raised when the liberation forces enter Al Qaim", said the text.
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The Iraqi Army, paramilitary Hashd al-Shaabi Brigade, tribal Sunni fighters and provincial police began the offensive, reports Xinhua news agency.
The Islamic State's control has been reduced to approximately 3 percent of Iraq as the Iraqi Security Forces mount their final offensive on the terror group inside the country.
The militants' Syrian stronghold, Raqqa, fell to USA -backed forces last week.
The offensive was launched from three sides, reports said.
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At the same time, U.K.'s Ministry of Defence has maintained there is "no evidence" any civilians were killed in at least 3,482 bombs and missiles the Royal Air Force dropped in Iraq and Syria, according to British news outlet, i News.
He pointed out that "Daesh gunmen were trying to block the progress of Iraqi forces towards the center of Al-Qaim".
The Britain-based Syrian Observatory for Human Rights war monitor said the Syrian army had advanced from T2 to reach 45km from the outskirts of Albu Kamal.
They have advanced mostly in areas to the west of the Euphrates River where they have captured the town of al-Mayadin and besieged the last Islamic State-held pockets of Deir al-Zor city.
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I would also like to apologise to the Dodgers organisation, the Astros , Major League Baseball and to all fans across the game". Then in the dugout after the home run, Gurriel stretched his eyes in a mocking manner and called Darvish a slur.
They've been losing all the big cities and towns, along the Euphrates River, with Syrian military pushing on the river's south shore, and Kurdish fighters taking the north shore.