The fight, expected to start after 4am BST, is being shown on Sky Box Office in the United Kingdom and Showtime Sports in the US.
'I wouldn't count a fight like this as a "fight".
Boxing and MMA cross in a clash which will generate eye-watering sums of money for both the fighters and promoters.
McGregor's total lack of boxing experience has proved a bone of contention for many in the build-up to the fight, but Joshua said he would enjoy taking on an MMA fighter, albeit with conditions. Major money has been placed on McGregor forcing the sportsbooks in Vegas to shift the odds.
Mayweather is coming out of retirement, but he is unlikely to have lost his knack for setting and controlling his own pace in a fight.
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However, he said, he would not be attending unless he was made a financial offer he could not refuse.
Mayweather and McGregor are expected to come face-to-face in Las Vegas for the first time at Wednesday's at the pre-fight press conference. I take it more of a show.
April 20, 2017 - He then posts another of him shadow boxing, with the caption: "Floyd may crap his jocks after all and if so I will go back to true fighting or just pick another boxer like Manny (Pacquiao) or something".
McGregor also agreed with the judges.
Boxing is a brutally simple sport and the intricate construction of a now fabled punch from McGregor will not, trust me, shift the axis of power from the 49 and zero prizefighter in the ring, in the opposite corner on the night.
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"Look what happened to him (Pacquiao) in that last fight", McGregor told MMAFighting.com.
"Easy work, easy work", said Mayweather.
As it turns out, McGregor has taken his trash-talking to the next level. If Mayweather, who has dedicated the fight "to all black people", loses his customary cool and tries to walk into the wheelhouse of his opponent, he could get caught with an unexpected big shot and blow the fight.
And with anticipation building ahead of the showdown at the T-Mobile Arena, McGregor is fully aware that he is approaching the defining point of his career.
Las Vegas is the mecca of boxing, so there is no better place to hold such an unusual and intriguing match-up.
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